M
General HealthStrong Evidence3rd Party Tested

Magnesium

Also known as: Magnesium Glycinate, Magnesium Citrate, Mg

The mineral involved in over 300 enzymatic reactions

8/10 Evidence Score

Primary Benefit

Sleep, Stress & Muscle Function

Standard Dose

200–400 mg elemental magnesium/day

Evidence

Certifications

USP Verified

Overview

Magnesium is an essential mineral involved in over 300 enzymatic processes, including energy production, protein synthesis, muscle and nerve function, and blood glucose control. Deficiency is widespread, affecting up to 50% of the population in developed countries.

Benefits & Evidence

  • Improves sleep quality and onset
  • Reduces muscle cramps and spasms
  • Supports blood pressure regulation
  • Aids blood glucose control
  • May reduce migraines

Clinical Study Summaries

The effect of magnesium supplementation on primary insomnia

2012

Journal of Research in Medical Sciences

Magnesium supplementation significantly improved sleep time, efficiency, and early morning awakening in elderly subjects.

Recommended Dosage

Standard Dose200–400 mg elemental magnesium/day
Minimum100 mg/day
Maximum420 mg/day (RDA upper end)
TimingEvening for sleep benefits; with food to reduce GI upset
Notes: Magnesium glycinate is well-absorbed and gentle on the stomach. Magnesium citrate is more affordable but may have laxative effects. Avoid oxide (poorly absorbed).

Side Effects & Interactions

Potential Side Effects
  • Loose stools or diarrhea (especially citrate form)
  • Nausea at high doses
  • Generally very safe at dietary levels
Drug & Nutrient Interactions
  • Antibiotics (tetracyclines, quinolones): take 2+ hours apart
  • Diuretics (may deplete magnesium further)
  • Proton pump inhibitors (may reduce absorption)

Who Should Consider It

Good candidates

  • Individuals with poor sleep or insomnia
  • Athletes with muscle cramps
  • People with high stress levels
  • Those with type 2 diabetes or insulin resistance
  • Migraine sufferers

Use caution or avoid

  • Those with kidney disease (reduced excretion)
  • People with myasthenia gravis
Medical Disclaimer

This information is for educational purposes only. It does not constitute medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you have health conditions or take medications.

Third-Party Testing

This supplement has products available with independent quality verification.

USP Verified
Evidence Breakdown
Overall Score8/10
Popularity8/10

Evidence Level

Strong

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