Green Tea Extract
Also known as: GTE, EGCG, Epigallocatechin Gallate, Camellia sinensis
A thermogenic polyphenol with synergistic fat-burning properties
Primary Benefit
Thermogenesis & Fat Oxidation
Standard Dose
400 to 500 mg EGCG per day
Evidence
Certifications
Overview
Green tea extract is concentrated from the leaves of Camellia sinensis and standardized for its active compounds, particularly epigallocatechin gallate (EGCG) and caffeine. The combination inhibits the enzyme catechol-O-methyltransferase (COMT), which prolongs norepinephrine signaling and sustains fat-burning, making it more effective than either compound alone.
Benefits & Evidence
- Inhibits COMT enzyme, prolonging fat-burning norepinephrine signaling
- Increases 24-hour energy expenditure by 3 to 4 percent
- Enhances fat oxidation, particularly during exercise
- Provides antioxidant protection via polyphenols
- May reduce visceral (abdominal) fat specifically
Clinical Study Summaries
Green tea extract thermogenesis-induced weight loss by epigallocatechin gallate inhibition of catechol-O-methyltransferase
1999Journal of Nutritional Biochemistry
EGCG inhibited COMT activity, increasing thermogenesis and fat oxidation beyond caffeine alone, establishing a distinct fat-burning mechanism.
Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure
1999American Journal of Clinical Nutrition
24-hour energy expenditure increased by 4 percent and fat oxidation by 10 percent compared to placebo in a controlled metabolic chamber study.
View studyRecommended Dosage
| Standard Dose | 400 to 500 mg EGCG per day |
| Minimum | 270 mg EGCG |
| Maximum | 800 mg EGCG/day |
| Timing | With meals to reduce GI discomfort; avoid on an empty stomach |
Side Effects & Interactions
Who Should Consider It
Good candidates
- Individuals seeking a mild, stimulant-gentle thermogenic
- People combining with caffeine for synergistic fat oxidation
- Those interested in antioxidant benefits alongside weight management
Use caution or avoid
- Individuals with liver conditions
- Those with iron deficiency anemia (take separately from iron)
- Pregnant or breastfeeding individuals